Metoprolol Succinate API Manufacturer in India

Molecular Formula

C34H56N2O10

Molecular Weight

652.8 g/mol

CAS Number

98418-47-4

Drug Class

Beta Blockers

Extended-release beta-blocker salt for cardiovascular applications.

Kodel Life manufactures Metoprolol Succinate API (CAS 98418-47-4) to IP, BP, USP, and EP grade specifications, purpose-built for extended-release tablet formulation. With a production capacity of 20 MT per month and full regulatory documentation support, Kodel Life is a trusted Metoprolol Succinate API supplier for pharmaceutical manufacturers across 21 countries.

ISO 9001:2015 certified. Exports to Asia, Europe, Americas & Africa.

Key Product Information

Generic Name Metoprolol Succinate
CAS Number 98418-47-4
Molecular Formula C34H56N2O10
Molecular Weight 652.8 g/mol
Drug Class Beta-1 Selective Adrenoceptor Antagonist
Dosage Form Suitability Extended-Release Tablets
Primary Application Cardiovascular: Hypertension, Angina, Heart Failure
Production Capacity 20 MT/Month
Grade
IP BP USP EP
Regulatory Documentation COA, DMF available on request

Applications & Use Cases

Cardiovascular Care — these medications are primarily used to treat heart-related conditions like high blood pressure (hypertension), chest pain, or heart failure. Metoprolol Succinate is manufactured with controlled-release grade specifications, supported by stability data and regulatory documentation for official filings..

What Is Metoprolol Succinate API?

Metoprolol Succinate is the extended-release salt form of Metoprolol, a cardioselective beta-1 adrenoceptor blocker used in the treatment of hypertension, chronic stable angina, and chronic heart failure. Unlike Metoprolol Tartrate, which releases rapidly, the succinate salt is formulated to deliver a controlled, once-daily dose profile, making it the preferred form for extended-release tablet manufacturing.

As an Active Pharmaceutical Ingredient (API), Metoprolol Succinate must meet precise particle size distribution, polymorphic purity, and dissolution specifications to ensure consistent drug release in the final dosage form. Kodel Life manufactures to all four major pharmacopoeial standards, providing formulation teams with a stable, verified starting material.

Metoprolol Succinate API for Tablet Formulation

For pharmaceutical manufacturers developing extended-release (ER) or modified-release (MR) oral solid dosage forms, the quality of the Metoprolol Succinate API directly determines dissolution profile, bioavailability, and regulatory acceptance. Kodel Life produces this API with controlled-release grade specifications supported by stability data and complete dossier documentation for regulatory filings.

Key Formulation-Grade Properties

Defined particle size distribution (PSD) for reproducible drug release

Controlled polymorphic form for dissolution consistency

Low moisture content and high chemical purity for long shelf stability

Full stability studies available to support 24- and 36-month shelf life claims

Compatible with standard matrix and membrane-controlled ER tablet platforms

Formulators sourcing Metoprolol Succinate API for tablet manufacture can request a Technical Data Package that includes COA, method validation data, and process-related impurity profiles.

Speak to our formulation support team

Why Source Metoprolol Succinate API from Kodel Life?

Kodel Life is a dedicated API manufacturing company based in Morbi, Gujarat, India. The facility operates under ISO 9001:2015 Quality Management Systems with FDA-compliant manufacturing practices, producing cardiovascular APIs at commercial scale.

Manufacturing and Quality Credentials

ISO 9001:2015 certified facility, Morbi, Gujarat, India

FDA-compliant manufacturing under current Good Manufacturing Practices (cGMP)

Full pharmacopoeial compliance: IP, BP, USP, and EP grades in a single source

In-house analytical testing with COA issued per batch

Drug Master File (DMF) documentation provided to support regulatory filings

Supply Chain Reliability

20 MT per month production capacity for Metoprolol Succinate

Consistent batch-to-batch quality backed by process controls

Dedicated export documentation team for customs and import compliance

Existing export relationships across Asia, Africa, Europe, and the Americas

Sample requests processed within 1-2 business days

Export-Ready

Kodel Life currently exports APIs to 21 countries across 5 continents, including USA, Germany, UK, Saudi Arabia, Japan, South Korea, Canada, and Brazil. Your regulatory team receives complete documentation at dispatch.

Regulatory Documentation and Compliance

Pharmaceutical procurement teams require more than product quality. They need a documentation package that satisfies national regulatory authorities without delays. Kodel Life provides:

Certificate of Analysis (COA) per batch, aligned to the requested pharmacopoeial standard

Drug Master File (DMF) or Dossier support for market authorisation submissions

Method validation data and reference standard certificates

Impurity profiles and related substance data per ICH Q3A guidelines

Stability data packages suitable for ASEAN, EU, and US regulatory submissions

Buyers registered with drug authorities in the EU, US, or other regulated markets can request an open or closed DMF reference letter as part of the procurement process.

Metoprolol Succinate vs Metoprolol Tartrate: Which API Do You Need?

Metoprolol is available as two salt forms — Succinate (extended-release) and Tartrate (immediate-release). The choice of salt determines the dosage form, release profile, dosing frequency, and regulatory pathway.

Parameter Metoprolol Succinate Metoprolol Tartrate
Salt Form Succinate (extended-release) Tartrate (immediate-release)
Release Profile Once-daily extended release Twice-daily immediate release
Primary Formulation Use ER tablets (XR/CR/MR) Immediate-release tablets, IV
CAS Number 98418-47-4 56392-17-7
Typical Strengths 25 mg, 47.5 mg, 50 mg, 95 mg, 100 mg, 200 mg ER 25 mg, 50 mg, 100 mg IR
Key Therapeutic Use Hypertension, CHF, Angina (once-daily) Acute MI, hypertension (rapid onset)
Regulatory Grade IP / BP / USP / EP IP / BP / USP / EP

Kodel Life manufactures both Metoprolol Succinate and Metoprolol Tartrate APIs. If your formulation project requires the immediate-release salt, visit the Metoprolol Tartrate API product page for specifications and sample requests.

Applications: Where Metoprolol Succinate API Is Used

Metoprolol Succinate API serves as the active ingredient in a range of cardiovascular pharmaceutical products globally. Procurement teams at generic pharmaceutical companies, contract development and manufacturing organisations (CDMOs), and branded generics manufacturers source this API for:

Extended-release (ER) antihypertensive tablets for once-daily dosing

Chronic heart failure (CHF) management formulations

Stable angina treatment products

Combination ER tablets (e.g., with Amlodipine or other antihypertensives)

Branded generic cardiovascular portfolios for regulated and emerging markets

How to Order Metoprolol Succinate API from Kodel Life

Kodel Life serves pharmaceutical buyers at all stages, from early development samples through commercial supply. The procurement process is straightforward:

1

Submit an enquiry or COA/DMF request via the contact form or WhatsApp (+91 75023 33335)

2

Receive product specifications, COA, and pricing within 1-2 business days

3

Request a sample for in-house testing (available on request)

4

Confirm order quantity, lead time, and export documentation requirements

5

Shipment with full documentation package, including COA, DMF, and shipping certificate

Get Metoprolol Succinate API Samples & Pricing

We work with formulation companies, contract manufacturers, and pharmaceutical distributors globally. Whether you need one tonne or twenty, the process starts with a conversation with our technical sales team.

Samples

Pre-qualified buyers

COA / DMF

On formal inquiry

20 MT/Month

Metoprolol Succinate capacity

21 Countries

USA, UK, EU, Africa, SEA

Interested in This Product?

Contact our team to discuss pricing, availability, and custom requirements.

Quality Certifications

ISO 9001:2015

Quality Management System

FDA Compliant

Regulatory Compliance

Medical Branding

Why Buyers Choose Kodel Life

20 MT/month manufacturing capacity

IP, BP, USP & EP grades available

ISO 9001:2015 certified QMS

Controlled-release grade specifications for ER tablet formulation

Batch-specific COA with every shipment

Export to 21 countries across 5 continents

DMF reference letter support for regulated markets

Sample requests answered within 1-2 business days

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Get All The Answer Of Your Question

Frequently Asked Questions

Kodel Life supplies Metoprolol Succinate API to IP, BP, USP, and EP pharmacopoeial grades. Buyers can specify the required standard when submitting an enquiry, and the COA will reflect the applicable monograph specifications.

Minimum order quantities depend on your specific requirements. Kodel Life accommodates both development-scale samples and commercial volumes up to 20 MT per month. Contact the team to discuss your project's quantity needs.

Yes. Kodel Life provides regulatory documentation, including DMF support for market authorisation submissions. Buyers can request a DMF reference letter as part of the procurement documentation package.

Kodel Life currently exports to 21 countries across Asia, Africa, Europe, and the Americas, including the USA, Germany, UK, Saudi Arabia, Japan, South Korea, Canada, Brazil, Thailand, and Bangladesh, among others.

Yes. Samples are available on request for qualified pharmaceutical manufacturers. Use the Request a Sample button on the product page, or contact the team directly via the enquiry form. The team typically responds within 1-2 business days.

Every Metoprolol Succinate API shipment is accompanied by a batch-specific Certificate of Analysis (COA), shipping documentation, and any regulatory support documents (DMF, stability data, impurity profiles) agreed at the time of order.

Metoprolol Succinate is the extended-release salt used in once-daily ER tablet formulations, while Metoprolol Tartrate is the immediate-release salt used in standard IR tablets and injectable products. The choice depends on your target dosage form and release profile.

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