NSAID / Analgesic — these are used for pain relief and to reduce inflammation. Piroxicam is a Non-Steroidal Anti-Inflammatory Drug (NSAID) used to treat pain and stiffness from conditions like arthritis. Manufactured meeting compendial tests for identity, assay, and related substances, packaged for bulk export from Gujarat, India.
Kodel Life manufactures Piroxicam API (CAS 36322-90-4) to IP, BP, USP, and EP pharmacopoeial standards from its ISO 9001:2015 certified facility in Morbi, Gujarat, India. This high-purity NSAID active pharmaceutical ingredient is purpose-built for anti-inflammatory and analgesic formulations across four dosage forms: capsules, topical gel, suppositories, and tablets.
With 10 MT per month production capacity and complete regulatory documentation, Kodel Life is a trusted Piroxicam API bulk supplier and pharmaceutical manufacturer serving buyers across 21 countries.
Request COA & DMF TodayISO 9001:2015 CertifiedShips to 21 Countries
Piroxicam is a long-acting, non-selective cyclooxygenase (COX) inhibitor belonging to the oxicam class of NSAIDs. It blocks prostaglandin biosynthesis through inhibition of both COX-1 and COX-2 enzymes, producing anti-inflammatory, analgesic, and antipyretic effects. Its plasma half-life of approximately 50 hours allows once-daily dosing, which sets it apart from shorter-acting NSAIDs and makes it particularly useful in managing chronic inflammatory conditions such as rheumatoid arthritis and osteoarthritis.
As an Active Pharmaceutical Ingredient, Piroxicam must meet stringent identity, assay, related substance, and particle size specifications across all four target pharmacopoeias. Kodel Life manufactures to IP, BP, USP, and EP monograph standards in a single cGMP-compliant facility, giving pharmaceutical buyers a batch-verified, fully documented starting material regardless of their target market.
Key Takeaway
Piroxicam's 50-hour half-life enables once-daily dosing in both oral and rectal dosage forms. This single-dose convenience is a formulation advantage that differentiates Piroxicam from most short-acting NSAIDs in the chronic pain and arthritis segment.
Piroxicam API for Multiple Dosage Form Formulations
Piroxicam is one of the most formulation-versatile NSAIDs in the generic pharmaceutical market. It is produced in four distinct dosage forms, each requiring specific API particle size, purity, and stability characteristics. Kodel Life supplies Piroxicam API with grade specifications and particle size data matched to each formulation pathway.
Oral Capsule Formulation (10 mg, 20 mg)
Hard gelatin capsules represent the dominant global Piroxicam formulation. API for direct capsule filling or granule encapsulation must meet consistent particle size and flow specifications.
Controlled PSD for reliable capsule fill weight and content uniformity
Polymorphic Form I stability confirmed throughout shelf life for dissolution consistency
Low moisture content compatible with direct-fill and wet granulation capsule processes
Assay of 99.0% or above per IP and USP monograph specifications
Topical Gel and Cream Formulation (0.5%)
Piroxicam 0.5% topical gel is widely prescribed across Asia, Europe, and the Middle East for localised musculoskeletal pain. Micronised API with a fine PSD is required for homogeneous dispersion in gel bases.
Micronised particle size for uniform dispersion in polyethylene glycol and carbomer gel bases
Extremely low related substance profile to minimise the risk of skin irritation
Solubility profile compatible with standard semi-solid excipients
Photostability data available to support photosensitivity risk labelling decisions
Suppository Formulation (20 mg)
Piroxicam suppositories are used when oral administration is not clinically appropriate, including post-surgical pain management and chronic arthritis flares.
Compatibility data available for Witepsol and cocoa butter suppository bases
Documented melting point behaviour for suppository mass temperature sensitivity
Batch records confirming in-vitro dissolution performance within the suppository matrix
Tablet Formulation (10 mg, 20 mg, Dispersible)
Conventional and dispersible Piroxicam tablets are produced across several regulated and emerging markets. Direct compression and wet granulation processes each have distinct API requirements.
Defined PSD for wet granulation tabletting compatibility
Flowability characteristics suitable for direct compression formulations
Stability data available to support 24- and 36-month shelf life claims on compressed dosage forms
Formulators receive a dosage form-specific Technical Data Package on request. This includes the COA, full impurity profile, method validation data, polymorphic form confirmation, and stability data matched to their target dosage form.
Kodel Life as a Piroxicam API Manufacturing Company
Kodel Life is a dedicated pharmaceutical API manufacturing company based in Morbi, Gujarat, India. The facility is ISO 9001:2015 certified and operates under FDA-compliant cGMP standards, producing NSAID, cardiovascular, and diuretic APIs at commercial scale for pharmaceutical buyers across 21 countries.
Quality and Analytical Capabilities
ISO 9001:2015 certified facility in Morbi, Gujarat, India
FDA-compliant cGMP manufacturing across all active API products
In-house analytical laboratory covering HPLC, IR identity, assay, related substances, PSD, and moisture
Compendial testing to IP, BP, USP, and EP pharmacopoeial monograph specifications
Batch-specific COA issued with every shipment; DMF documentation available for all commercial APIs
ICH Q3A-compliant impurity profiling and ICH Q1A stability data available on request
Multi-Product Portfolio: One Qualified Supplier for Your Full API Requirement
Kodel Life is not a single-molecule manufacturer. The same ISO-certified facility produces a full portfolio of cardiovascular and diuretic APIs, enabling pharmaceutical buyers to consolidate vendor qualifications and reduce regulatory audit overhead.
IP/BP/USP/EP grade — antihypertensive and combination formulation supply
Piroxicam API
10 MT/Month
NSAID
This page — capsule, topical gel, suppository, and tablet grade supply
Qualifying one API supplier for cardiovascular, diuretic, and NSAID APIs reduces audit cycles, simplifies documentation management, and streamlines procurement. Kodel Life provides a single regulatory dossier framework across all five APIs.
Kodel Life is an established Piroxicam API bulk supplier from India, with active export relationships across 21 countries on five continents. Bulk supply is available from development-scale samples through to commercial orders of up to 10 MT per month.
Export Markets
Southeast Asia
Thailand, Vietnam, Myanmar, Malaysia, Philippines
South Asia
Sri Lanka, Bangladesh, Nepal, Pakistan
Middle East
UAE, Saudi Arabia, Jordan
Africa
Kenya, Tanzania, Nigeria, Ethiopia, South Africa
Europe and CIS
Germany, Russia, Ukraine
Americas
USA, Brazil, Canada
What Every Bulk Shipment Includes
Batch-specific Certificate of Analysis (COA) to the specified pharmacopoeial standard
Drug Master File (DMF) reference letter or open DMF support for regulatory submissions
Stability data per ICH Q1A: six-month accelerated and 12-month long-term results
Impurity profile per ICH Q3A: identification and qualification thresholds met
Shipping and customs documentation for destination market import compliance
Material Safety Data Sheet (MSDS/SDS) for hazardous material handling compliance
Bulk Supply Lead Time
Development samples are dispatched within one to two business days of confirmed request. Commercial bulk orders are supported with dedicated export documentation and a regulatory affairs liaison. Contact the team via the enquiry form or WhatsApp (+91 75023 33335) to discuss specific quantities and lead times.
Regulatory Documentation for Global Markets
Piroxicam API supplied into regulated markets, including the EU, US, Canada, Japan, and Australia, requires a complete regulatory dossier beyond the Certificate of Analysis. Kodel Life provides the full documentation stack as standard.
Certificate of Analysis (COA) per batch: IP, BP, USP, or EP monograph as specified by the buyer
Drug Master File (DMF) support: Type II DMF filing for US submissions; ASMF for EU CTD submissions
Impurity profiles per ICH Q3A: all related substances identified and qualified
Residual solvent data per ICH Q3C: Class 2 and Class 3 solvents profiled per batch
Stability data per ICH Q1A: accelerated (40°C/75% RH) and long-term (25°C/60% RH) conditions
Method validation certificates per ICH Q2R1
Polymorphic form confirmation and particle size distribution reports
Regulatory affairs teams working on EU CTD or US ANDA submissions can request an open or closed DMF reference letter. Buyers in ASEAN markets receive COA plus country-specific import compliance support from the Kodel Life export documentation team.
Piroxicam vs Meloxicam: Choosing the Right NSAID API
Piroxicam and Meloxicam are both oxicam-class NSAIDs. Pharmaceutical procurement teams frequently evaluate both when building or expanding an NSAID API portfolio. The comparison below covers the key decision factors.
Established off-patent generic, OTC in some markets
Premium generic in musculoskeletal segment
Kodel Life Supply
Yes: IP/BP/USP/EP, 10 MT/Month
Intermediate available (Meloxicam/Piroxicam Intermediate)
Kodel Life also supplies the Meloxicam/Piroxicam Intermediate, the shared chemical precursor for both API synthesis pathways. Manufacturers producing both NSAIDs can source the intermediate from the same qualified supplier, reducing vendor qualification overhead.
Where Piroxicam API Is Used
Piroxicam API is sourced by generic pharmaceutical companies, NSAID-focused contract development and manufacturing organisations (CDMOs), branded generics manufacturers, and OTC product developers. Common applications include:
Hard gelatin capsules (10 mg, 20 mg) for rheumatoid arthritis and osteoarthritis management
Topical gel (0.5%) for localised musculoskeletal, joint, and soft tissue pain
Suppositories (20 mg) for post-surgical and chronic pain management where oral dosing is not appropriate
Dispersible and standard tablets for paediatric and geriatric anti-inflammatory treatment
Combination NSAID formulations with antacid or gastroprotective co-formulation ingredients
OTC analgesic and anti-inflammatory products in markets where Piroxicam holds OTC approval
Veterinary anti-inflammatory formulations, including use in veterinary oncology protocols
How to Order Piroxicam API from Kodel Life
Kodel Life serves pharmaceutical buyers from early development through commercial bulk supply. The process runs in five steps:
1
Submit an enquiry via the contact form or WhatsApp (+91 75023 33335). Specify your target dosage form and pharmacopoeial standard.
2
Receive the COA, full specification sheet, and pricing within one to two business days.
3
Request a development sample or dosage form-specific Technical Data Package for in-house testing and formulation work.
4
Confirm order quantity, packaging specification, and export documentation requirements.
5
Shipment dispatched with the complete documentation package: COA, DMF reference letter, stability data, and SDS.
Ready to Source Piroxicam API from India?
Kodel Life works with generic pharmaceutical companies, CDMOs, branded generics manufacturers, and trading houses sourcing NSAID APIs from India. Whether you need a development sample, a full regulatory dossier, or a long-term bulk supply contract, the team responds within one to two business days.
Kodel Life supplies Piroxicam API to IP, BP, USP, and EP pharmacopoeial grades. Buyers specify the required standard at enquiry stage, and the batch COA confirms compliance with the applicable monograph, covering identity, assay, related substances, residual solvents, and particle size distribution.
Production capacity for Piroxicam API is 10 MT per month. This accommodates development-scale sample requests as well as long-term commercial bulk supply contracts. Contact the team to confirm availability and lead times for your specific volume requirement.
Yes. Kodel Life supplies micronised Piroxicam API suitable for 0.5% topical gel formulation. The API meets fine particle size distribution requirements for homogeneous dispersion in PEG and carbomer-based gel bases. Photostability data and related substance profiles are available on request. Specify 'topical grade' in your enquiry to receive the matching specification sheet.
Kodel Life's Piroxicam API is suitable for four dosage forms: hard gelatin capsules, topical gel and cream, suppositories, and conventional or dispersible tablets. Dosage form-specific Technical Data Packages are available on request, covering particle size data, polymorphic form confirmation, stability data, and formulation compatibility information.
Standard documentation includes a batch COA to the specified pharmacopoeial standard, DMF or ASMF support for regulatory submissions, impurity profiles per ICH Q3A, residual solvent data per ICH Q3C, stability data per ICH Q1A, and method validation certificates per ICH Q2R1. Market-specific documentation for USFDA, EMA, or ASEAN authorities is available on request.
Yes. Kodel Life is a multi-product pharmaceutical API manufacturing company. The same ISO-certified facility produces Furosemide API (20 MT/month), Metoprolol Succinate API (20 MT/month), Metoprolol Tartrate API (62 MT/month), and Hydrochlorothiazide API (10 MT/month). Pharmaceutical buyers can consolidate cardiovascular and NSAID API procurement to a single qualified vendor.
Kodel Life exports Piroxicam API to 21 countries across Asia, Africa, Europe, and the Americas. Active markets include Thailand, Bangladesh, UAE, Saudi Arabia, Germany, USA, Canada, Brazil, Kenya, South Africa, Sri Lanka, Vietnam, and the Philippines, among others.
Yes. Kodel Life supplies the Meloxicam/Piroxicam Intermediate, the shared chemical precursor used in both Piroxicam and Meloxicam API synthesis. Manufacturers producing both NSAIDs can source the intermediate from the same qualified supplier, reducing vendor qualification burden and simplifying regulatory documentation.
Market Insights
