Sodium Furosemide is the sodium-salt intermediate stage of Furosemide, a high-ceiling loop diuretic used for oedema linked to heart, liver, or kidney conditions, and for hypertension. Kodel Life manufactures it under ISO 9001:2015 controls, with documented process validation and batch traceability.
Furosemide, one of the world's most widely used loop diuretics, reaches its finished acid form through a sodium-salt intermediate stage. Getting that stage right, consistent crystallization, consistent purity, is what keeps downstream Furosemide batches predictable.
At Kodel Life, we produce Sodium Furosemide in IP, BP, USP, and EP grades with a monthly output of 62 MT. Our manufacturing plant operates under ISO 9001:2015 certification and supplies to pharmaceutical companies in 21 countries across 5 continents.
This page covers everything a pharma buyer, formulator, or procurement head needs to know before choosing a Sodium Furosemide supplier.
What Is Sodium Furosemide?
Chemical Profile & Synonyms
Sodium Furosemide is the sodium-salt intermediate stage of furosemide, the anthranilic-acid-derivative loop diuretic. Manufacturers carry this intermediate forward into the finished Furosemide API through an acidification and crystallization step.
Parameter
Value
Generic Name
Sodium Furosemide
CAS Number
41245-30-5
Molecular Formula
Confirmed on Certificate of Analysis
Molecular Weight
Confirmed on Certificate of Analysis
Application
Loop diuretic intermediate
Pharmacopoeial Grades
IP, BP, USP, EP
Physical Form
White to off-white crystalline solid
From Sodium Furosemide to Finished Furosemide API
Furosemide manufacturers take Sodium Furosemide through an acidification step to precipitate and crystallize the finished free-acid API, which is then dried, milled, and tested against pharmacopoeial limits before release.
The most common issue we encounter with loop-diuretic intermediates is inconsistent crystallization yield between batches. Kodel Life controls this through fixed process parameters and batch traceability, so buyers get consistent particle characteristics batch after batch.
Where This Intermediate Sits in the Synthesis Route
A quick map of how Sodium Furosemide moves from raw feedstock to finished therapy, so you can confirm this is the stage you actually need before ordering.
Starting Materials
Sodium Furosemide (this intermediate)
Furosemide API
Acidification & crystallization
Oedema & hypertension therapy
Why Demand for Loop Diuretic Intermediates Keeps Rising
Furosemide has been on the WHO Essential Medicines List for decades, and the intermediates behind it see the same steady demand growth.
Rising incidence of congestive heart failure (CHF) worldwide
According to WHO estimates, approximately 1.28 billion adults aged 30–79 years live with hypertension worldwide
Increasing use of generic Furosemide formulations in emerging markets
Expansion of hospital-based care in Africa, Southeast Asia, and South America, where loop diuretics see heavy acute-care use
India manufactures over 20% of the world's generic APIs and intermediates by volume. Several of the largest Furosemide intermediate manufacturers operate out of Gujarat and Maharashtra, benefiting from established chemical supply chains and skilled pharma workforces.
Sodium Furosemide Technical Specifications
Grades Available: IP, BP, USP, EP
Procurement teams sourcing Sodium Furosemide for regulated markets need the right pharmacopoeial grade. Here is what each covers:
IP
Indian Pharmacopoeia
Required for products marketed in India and several South Asian and African markets.
BP
British Pharmacopoeia
Accepted across the UK, the Commonwealth, and many EU countries.
USP
United States Pharmacopeia
Mandatory for products entering the US market and many Latin American regulators.
EP
European Pharmacopoeia
Required for EU market access; often accepted alongside BP.
Kodel Life supplies all four grades from a single manufacturing facility, which reduces sourcing complexity for exporters managing multi-market compliance.
Pharmacopoeial Standards & Purity
Every batch of Sodium Furosemide we release undergoes testing per pharmacopoeial specifications, including:
Assay (HPLC) against the applicable pharmacopoeial limit
Related substances and impurity profiling
Residual solvents (ICH Q3C Class 2 and 3)
Heavy metals and elemental impurities (ICH Q3D)
Particle size distribution
Water content by Karl Fischer titration
Certificate of Analysis (COA), technical specifications, and regulatory documentation support are available upon request. Documentation availability may vary depending on the destination market and regulatory requirements.
Packaging, Storage & Handling
Packaging
Double-lined HDPE drums with moisture-proof inner lining, typical of Kodel Life's other bulk intermediates. Exact pack size is confirmed at quotation.
Storage
Cool, dry place away from direct light. Recommended temperature below 25°C.
Shelf Life
Confirmed on the Certificate of Analysis for each batch; consistent with the storage conditions above.
Transport classification and export documentation, including COA and MSDS, are confirmed with each shipment.
Why Buyers Choose Kodel Life for Sodium Furosemide
Pharmaceutical companies sourcing this intermediate need more than competitive pricing. They need consistent quality, reliable documentation, and dependable supply continuity.
Manufacturing capacity of 62 MT per month
Available in IP, BP, USP, and EP grades
ISO 9001:2015 certified quality management system
Batch-specific Certificate of Analysis (COA)
Consistent crystallization yield and batch traceability
Export supply experience across multiple international markets
Technical support for formulation and procurement teams
Documentation support available for qualified buyers
Why Source Sodium Furosemide from India?
India accounts for a significant share of global intermediate and API exports, and the reasons are structural rather than coincidental.
Regulatory Infrastructure
India has the second-highest number of US FDA-approved manufacturing sites outside the US.
Cost Advantage
Labor, raw material, and utility costs in India remain significantly lower than in Europe or North America without compromising output quality.
Scale
Large Indian manufacturers can handle multi-tonne monthly orders with consistent batch-to-batch quality.
Speed to Market
Established logistics corridors from JNPT, Mundra, and Chennai ports reduce lead times for global buyers.
Documentation Readiness
Leading intermediate and API manufacturers often maintain regulatory documentation such as DMFs, ASMFs, CEPs, or market-specific dossiers depending on their target export markets.
For buyers in the US, EU, Southeast Asia, or Africa sourcing an intermediate supplier for export, India-based manufacturers offer the most practical combination of price, scale, and compliance.
Where Sodium Furosemide Is Used Downstream
This intermediate feeds a single, well-defined downstream API.
Furosemide API
Furosemide manufacturers take Sodium Furosemide through an acidification step to precipitate and crystallize the finished free-acid API, used in tablets, oral solution, and IV/IM injection formulations for oedema and hypertension.
Explore Related Manufacturing Capabilities
In addition to this intermediate, Kodel Life supports pharmaceutical companies through a broad range of manufacturing and documentation services.
API Manufacturing Services
Intermediates Supply at Scale
Quality Control & Testing
Export Documentation Support
Pharmaceutical Contract Manufacturing
Comparing Sodium Furosemide Suppliers: What Actually Matters
Not every intermediate supplier will fit every buyer's situation. Here is a practical comparison of the key variables:
Factor
What to Check
Why It Matters
Certifications
ISO 9001, FDA compliance, EDQM CEP
Determines which regulated markets you can sell into
Documentation Availability
COA with every batch; DMF/CEP reference where applicable
Needed if your own API filing references this intermediate
Production Capacity
MT per month, surge capacity
Avoids supply disruptions during peak demand
Grades Offered
IP / BP / USP / EP
Must match your target market's pharmacopoeial requirements
Lead Time
Standard and expedited timelines
Affects planning cycles and inventory management
Synonym Accuracy
CAS number matched to every trade name used
Prevents ordering the wrong impurity or intermediate by mistake
Export Track Record
Countries served, logistics partners
Reduces risk of first-shipment compliance issues
Kodel Life checks every box in this table. We have been exporting to 21 countries and maintain active documentation for all four pharmacopoeial grades.
What to Look for When Choosing a Sodium Furosemide Manufacturer
Certifications: ISO, FDA, EDQM
A certificate is only as good as the audit trail behind it. When evaluating any intermediate manufacturer, ask specifically for:
ISO 9001:2015 scope certificate covering this specific intermediate line
FDA establishment registration number (verifiable on FDA.gov)
EDQM CEP (Certificate of Suitability) if you target European markets
Kodel Life holds ISO 9001:2015 certification and follows documented quality management systems designed to support pharmaceutical intermediate manufacturing. Product documentation, including COA and technical specifications, is available to qualified buyers upon request.
COA & Documentation Availability
A Drug Master File (DMF) is a submission to a regulatory authority (USFDA, EMA, PMDA) that contains confidential details about the manufacturing process, facilities, and controls behind a drug substance or key intermediate. Buyers planning US or EU market launches should confirm whether their supplier's documentation can be referenced in a New Drug Application or Abbreviated New Drug Application.
At Kodel Life, COA and DMF-linked documentation is available upon request for qualified buyers. Our team supports the technical transfer process from the first enquiry.
Production Capacity & Lead Times
62 MT/Month
Sodium Furosemide production capacity
62 MT/Month
Total capacity across all products
2–4 Weeks
Standard lead time for stocked material
Custom batch orders take 6 to 8 weeks depending on specifications.
Common Mistakes Pharma Buyers Make When Sourcing Sodium Furosemide
1
Confirming the CAS number against the COA, not just the page
CAS numbers for furosemide salt forms vary across registries. Always cross-check the number on your Certificate of Analysis before filing paperwork against it.
2
Treating Sodium Furosemide as the finished drug
Sodium Furosemide is an intermediate stage, not the active pharmaceutical ingredient dispensed to patients. Confirm you need the intermediate, not the finished Furosemide API, before ordering.
3
Not confirming the grade before ordering
An IP-grade intermediate cannot support a US ANDA filing. Always map the grade to your regulatory target market before placing an order.
4
Overlooking crystallization consistency in supplier vetting
Ask prospective suppliers for batch-to-batch particle size and yield data specifically for the intermediate stage, not only for the finished API.
5
Skipping supplier audits
Even for small initial orders, request a supplier self-audit questionnaire or arrange a remote audit for the intermediate line specifically.
Get Sodium Furosemide Samples & Pricing
If you are sourcing Sodium Furosemide in bulk for formulation, further synthesis, or export, our team can walk you through grade options, documentation packages, and dispatch timelines. Whether you need one tonne or twenty, the process starts the same way: a conversation with our technical sales team.
Samples
Available for pre-qualified buyers
COA / DMF
Available upon formal inquiry
62 MT/Month
Sodium Furosemide capacity
21 Countries
USA, UK, EU, Africa, SEA
Reach out through the enquiry form or contact us directly. We respond within 1 to 2 business days.
Interested in This Product?
Contact our team to discuss pricing, availability, and custom requirements.
Quality Certifications
ISO 9001:2015
Quality Management System
FDA Compliant
Regulatory Compliance
Why Buyers Choose Kodel Life
Manufacturing capacity of 62 MT per month
Available in IP, BP, USP, and EP grades
ISO 9001:2015 certified quality management system
Batch-specific Certificate of Analysis (COA)
Consistent crystallization yield and batch traceability
Export supply experience across multiple international markets
Technical support for formulation and procurement teams
It is used as a chemical intermediate in the manufacture of Furosemide, a loop diuretic prescribed for oedema, hypertension, and related fluid-retention conditions.
No. Sodium Furosemide is an intermediate stage in Furosemide API synthesis, not the finished active pharmaceutical ingredient dispensed to patients.
41245-30-5, as listed on this page. Buyers preparing a regulatory filing should confirm this number against the Certificate of Analysis for their specific batch.
Kodel Life supplies Sodium Furosemide at IP, BP, USP, and EP grade.
62 MT per month.
Yes. Every batch ships with a Certificate of Analysis, and Drug Master File access is available on request.
Yes. Kodel Life provides samples to pre-qualified buyers for evaluation. Submit your enquiry through the contact page or the form on this page and specify your target grade and quantity.
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